Emzor Erythro Suspension is an oral antibiotic formulation containing Erythromycin as its active ingredient. This macrolide antibiotic provides effective treatment for various bacterial infections in a suspension form that’s particularly suitable for children and patients who have difficulty swallowing tablets.
Uses
Emzor Erythro Suspension treats respiratory tract infections including pharyngitis, tonsillitis, bronchitis, and pneumonia. It is effective against skin and soft tissue infections, whooping cough, diphtheria, Legionnaires’ disease, and certain sexually transmitted infections. It serves as an alternative for patients allergic to penicillin.
Benefits
- Broad-spectrum antibacterial activity
- Effective against gram-positive and some gram-negative bacteria
- Suitable for penicillin-allergic patients
- Palatable suspension form improves compliance
- Convenient dosing for pediatric patients
- Good tissue penetration
- Minimal disruption to gut flora compared to some antibiotics
- Well-established safety profile
How It Works
Emzor Erythro Suspension works by binding to bacterial ribosomes, specifically the 50S subunit, inhibiting protein synthesis. This bacteriostatic action prevents bacterial growth and reproduction, allowing the body’s immune system to effectively eliminate the infection.
Duration of Action
Erythromycin reaches peak plasma concentrations within 1-2 hours after oral administration. The medication maintains therapeutic levels for approximately 6-8 hours, necessitating multiple daily doses. The half-life ranges from 1.5-2 hours in patients with normal liver function.
Dosage
Age Group | Recommended Dosage | Frequency |
---|---|---|
Adults | 250-500mg | Every 6-8 hours |
Children | 30-50mg/kg/day | Divided every 6-8 hours |
Infants | 20-40mg/kg/day | Divided every 6-8 hours |
Warnings
Erythro Suspension should not be used in patients with known hypersensitivity to erythromycin or other macrolide antibiotics. Use with caution in patients with liver disease, myasthenia gravis, or history of QT interval prolongation. May cause infantile hypertrophic pyloric stenosis in young infants.
Side Effects
Common side effects include gastrointestinal disturbances such as nausea, vomiting, abdominal pain, and diarrhea. Less common effects include allergic reactions, reversible hearing loss with high doses, and liver function abnormalities. Prolonged use may lead to superinfection.
Pregnancy and Breastfeeding
Emzor Erythro Suspension is generally considered safe during pregnancy and is classified as FDA pregnancy category B. It is also compatible with breastfeeding, as only small amounts pass into breast milk. Consult healthcare providers before use during pregnancy or while breastfeeding.
Interactions
- Statins (increased risk of myopathy)
- Warfarin (enhanced anticoagulant effect)
- Theophylline (increased theophylline levels)
- Digoxin (increased digoxin concentration)
- Carbamazepine (elevated carbamazepine levels)
- Ergotamine (increased risk of ergotism)
- Triazolam and other benzodiazepines (increased sedation)
- Sildenafil (increased exposure and effects)
Precautions
Take Erythro Suspension on an empty stomach, 1 hour before or 2 hours after meals for optimal absorption. Complete the full course of treatment even if symptoms improve. Shake well before each use. Store in refrigerator if indicated on package. Notify healthcare provider of all medications being taken to prevent interactions.
Important Information
Erythro Suspension should be taken exactly as prescribed to ensure effectiveness and prevent bacterial resistance. The suspension should be shaken well before measuring each dose. Improvement should be noticeable within a few days, but the complete course must be finished to prevent reinfection or resistant bacteria development.
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